Inflammatory Signatures of Pathogenic and Non-Pathogenic Leptospira Infection in Susceptible C3H-HeJ Mice
نویسندگان
چکیده
منابع مشابه
Molecular detection of pathogenic Leptospira in Iran
Leptospirosis is an acute infectious, systemic and septisemic disease which had recent outbreaks in some parts of Iran especially in north provinces. Rapid detection is a critical step for treatment and control of this disease. In this research a PCR based method was evaluated for detection of Iranian local endemic serovars. All reported endemic serovars of Leptospira including Leptospira gri...
متن کاملLethal infection of C3H/HeJ and C3H/SCID mice with an isolate of Leptospira interrogans serovar copenhageni.
Leptospira interrogans serovar Copenhageni strain RJ16441, a blood isolate from humans with the severe pulmonary form of leptospirosis, has previously been shown to cause fatal pulmonary hemorrhage in guinea pigs and asymptomatic chronic renal tubular colonization with urinary shedding in rats. In this study, RJ16441 caused lethal infection of both C3H/HeJ and C3H/SCID mice, but no hemorrhagic ...
متن کاملDifference in susceptibility to gram-negative urinary tract infection between C3H/HeJ and C3H/HeN mice.
The difference in susceptibility to urinary tract infection between C3H/HeJ and C3H/HeN mice was tested for with gram-negative strains differing in lipopolysaccharide composition. Recently, impaired clearance of Escherichia coli from the kidney of C3H/HeJ compared to C3H/HeN mice was shown to be correlated with the LPS low responsiveness. In this study, a difference in clearance from the kidney...
متن کاملmolecular detection of pathogenic leptospira in iran
leptospirosis is an acute infectious, systemic and septisemic disease which had recent outbreaks in some parts of iran especially in north provinces. rapid detection is a critical step for treatment and control of this disease. in this research a pcr based method was evaluated for detection of iranian local endemic serovars. all reported endemic serovars of leptospira including leptospira gripp...
متن کاملResponses of Human Endothelial Cells to Pathogenic and Non-Pathogenic Leptospira Species
Leptospirosis is a widespread zoonotic infection that primarily affects residents of tropical regions, but causes infections in animals and humans in temperate regions as well. The agents of leptospirosis comprise several members of the genus Leptospira, which also includes non-pathogenic, saprophytic species. Leptospirosis can vary in severity from a mild, non-specific illness to severe diseas...
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ژورنال
عنوان ژورنال: Frontiers in Cellular and Infection Microbiology
سال: 2021
ISSN: 2235-2988
DOI: 10.3389/fcimb.2021.677999